NCT02316561

Single Dose Ablative Radiation Treatment for Early-Stage Breast Cancer

Single Dose Ablative Preoperative Radiation Treatment for Early-Stage Breast Cancer in Elderly Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: UMC Utrecht · Academic / Other
• Sex: Female
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to investigate the feasibility of a preoperative, single dose, ablative partial breast radiation treatment in patients with early-stage breast cancer.

Detailed description

A total of twenty-five patients will be treated with a single dose preoperative ablative radiation treatment. After a vigilant follow-up with MRI, breast conserving surgery will be performed 6 months after the ablative radiation treatment. The total follow-up time is 10 years. This study aims to present an ablative radiotherapy treatment approach that could resolve to some extent the disadvantages of current breast conserving treatment in elderly low-risk breast cancer patients who are currently not treated according to guidelines due to co-morbidity.

Conditions

• Breast Neoplasm

Interventions

Type	Name	Description
RADIATION	Single dose ablative radiotherapy	A single dose ablative radiotherapy will be delivered prior to surgery

Timeline

• Start date: 2014-10-01
• Primary completion: 2018-04-01
• Completion: 2018-04-01
• First posted: 2014-12-15
• Last updated: 2018-07-20

Locations

1 site across 1 country: Netherlands