NCT02314806

Gentamicin Versus Clindamycin Versus Normal Saline Lavage in Axilla

Effect of Gentamicin Versus Clindamycin Versus Normal Saline Lavage of the Axillary Surgical Bed After Lymph Node Dissection on Drainage Discharge Volume

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 51 (actual)
• Sponsor: Hospital General Universitario Elche · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

The patients undergoing axillary lymph node dissection were randomized into 3 groups: patients undergoing lavages with normal saline (Group 1), patients undergoing lavage gentamicin solution (Group 2) and patients undergoing lavage with a clindamycin solution (Group 3). Drainage volume discharge is investigated

Detailed description

The patients undergoing axillary lymph node dissection were randomized into 3 groups: patients undergoing 2 lavages with 500 ml normal saline (Group 1), patients first undergoing lavage with 500 ml normal saline followed by a second lavage with a 500 ml of a gentamicin (240 mg) solution (Group 2) and patients first undergoing lavage with 500 ml normal saline followed by a second lavage with 500ml of a clindamycin (600mg) solution (Group 3). Drainage volume discharge is investigated

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DRUG	Irrigation with gentamicin solution	The surgical bed is irrigated with a gentamicin solution
DRUG	Irrigation with Clindamycin solution	The surgical bed is irrigated with a clindamycin solution
DRUG	Irrigation with Normal saline	The surgical bed is irrigated with normal saline

Timeline

• Start date: 2013-01-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2014-12-11
• Last updated: 2014-12-11