NCT02314234

Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

Influence of Sugammadex on Facial Nerve Monitoring in Parotid Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Detailed description

Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Conditions

• Injury to Nerve During Surgery

Interventions

Type	Name	Description
DRUG	sugammadex (Bridion)	single dose of sugammadex at skin incision

Timeline

• Start date: 2012-01-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2014-12-11
• Last updated: 2016-02-25

Locations

1 site across 1 country: Taiwan