Trials / Completed
CompletedNCT02311075
Mechanisms of Endothelial Dysfunction in Type 2 Diabetes
Determination of the Mechanisms Involved in Conduit Artery Endothelial Dysfunction in Type 2 Diabetes
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 48 (actual)
- Sponsor
- University Hospital, Rouen · Academic / Other
- Sex
- All
- Age
- 30 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
Endothelial dysfunction of conduit arteries plays an important role in the development of cardiovascular complications associated with type 2 diabetes. In order to propose targeted therapeutic approaches, this study aim to determine the mechanisms involved in endothelial dysfunction of conduit arteries in these patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Blood samples | Blood samples will be performed at baseline and during endothelial stimulation by hand skin heating to quantify metabolites of NO, EETs, ET-1 and ROS |
Timeline
- Start date
- 2014-12-01
- Primary completion
- 2016-12-01
- Completion
- 2016-12-01
- First posted
- 2014-12-08
- Last updated
- 2017-06-14
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02311075. Inclusion in this directory is not an endorsement.