NCT02308709

Novel Lung Functional Imaging for Personalized Radiotherapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study is to assess the safety and feasibility of personalized radiotherapy with four-dimensional (4D) computed tomography (CT)-based pulmonary ventilation imaging, which selectively avoids irradiating highly-functional lung regions.

Detailed description

In this clinical trial, the investigators will assess the safety and feasibility of 4D CT ventilation image-guided personalized radiotherapy. The investigators will deliver personalized radiotherapy treatments that selectively avoid irradiating highly-functional lung regions for lung cancer patients, and follow up patients to assess the safety and feasibility. The primary hypothesis to be tested is: 4D CT ventilation image-guided personalized radiotherapy can be delivered safely for lung cancer.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
RADIATION	Ventilation image-guided radiotherapy	Patient's treatment plan will be created and optimized to minimize the dose to highly-functional lung regions

Timeline

• Start date: 2014-09-15
• Primary completion: 2020-11-19
• Completion: 2021-11-19
• First posted: 2014-12-04
• Last updated: 2022-11-10
• Results posted: 2022-11-10

Locations

1 site across 1 country: United States