NCT02303496

Autologous Platelet-Rich Plasma Cream for Photoaging and Chronological Skin Aging

The Effects of Autologous Platelet-Rich Plasma Cream on Photoaging and Chronological Skin Aging

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Acibadem University · Academic / Other
• Sex: Female
• Age: 35 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Human skin undergoes some morphological changes with the effects of chronological aging and photoaging, these are especially remarkable in the facial skin. Changes in pigmentation, sallowness, deep wrinkling, laxity and elastosis are the main changes seen in photoaging and chronologic aging of skin. With the increasing demand, it needs to provide new approach for the prevention and treatment of these morphological changes. Fibroblasts have a key role on skin aging. It is known that platelet rich plasma activates the fibroblasts and increases the synthesis of collagen and other type of matrix components. Because of these specialities, platelet rich plasma is thought to be effective on skin aging.

Detailed description

Clinical evaluation of the patients will be done for five times during 3 months. 0th day (Basal), 7th day, 15th day, 45th day and 105th day.

Conditions

• Chronological Aging of Skin
• Photoaging of Skin

Interventions

Type	Name	Description
BIOLOGICAL	Platelet Rich Plasma Cream	Cream Containing Platelet Rich Plasma and Oleaginous Base
BIOLOGICAL	Placebo - Sterile Water Cream	Cream Containing Sterile Water and Oleaginous Base

Timeline

• Start date: 2014-12-01
• Primary completion: 2015-03-01
• Completion: 2015-05-01
• First posted: 2014-12-01
• Last updated: 2014-12-01

Locations

2 sites across 1 country: Turkey (Türkiye)