Clinical Trials Directory

Trials / Completed

CompletedNCT02300233

The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia

The COMPASS Study: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of ISIS 304801 Administered Subcutaneously to Patients With Hypertriglyceridemia

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
114 (actual)
Sponsor
Ionis Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of volanesorsen given for 26 weeks in participants with Hypertriglyceridemia.

Conditions

Interventions

TypeNameDescription
DRUGVolanesorsen300 mg volanesorsen administered subcutaneously once-weekly for 26 weeks.
DRUGPlaceboVolanesorsen-matching placebo administered subcutaneously once-weekly for 26 weeks.

Timeline

Start date
2015-02-05
Primary completion
2016-07-27
Completion
2017-01-24
First posted
2014-11-24
Last updated
2022-04-13
Results posted
2022-04-13

Locations

45 sites across 6 countries: United States, Canada, France, Germany, Netherlands, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT02300233. Inclusion in this directory is not an endorsement.