NCT02299986

An InnovaTive Approach to Ventilator-Induced Diaphragmatic Dysfunction

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 56 (actual)
• Sponsor: University Hospital, Antwerp · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

'Ventilator-Induced Diaphragmatic Dysfunction (VIDD) was originally described by Vassilakopoulos and Petrof in 1998, where it is used to cover the effects of mechanical ventilation and respiratory muscle unloading on the diaphragm. A recent article by Grosu and colleagues has demonstrated that the thickness of the diaphragm decreases with about 6% a day in a small cohort of mechanically ventilated patients. This is a longitudinal, single-centre, observational cohort study to examine the long-term effects of invasive mechanical ventilation on the diaphragm, and to study the risk factors associated with VIDD.

Conditions

• Ventilator-induced Diaphragm Dysfunction
• VIDD

Interventions

Type	Name	Description
OTHER	Ultrasound measurement	Thickness measurement through ultrasound. The investigators will perform daily ultrasound measurements to assess the evolution in thickness during mechanical ventilation

Timeline

• Start date: 2013-04-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2014-11-24
• Last updated: 2015-06-24

Locations

1 site across 1 country: Belgium