NCT02298101

Comparison of Lung Deposition With the Aeroneb Solo Adapter and a Standard Jet Nebulizer by SPECT-CT

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: Male
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

Aeroneb Solo Adapter is a vibrating-mesh nebulizer Aeroneb Solo combined to a spacer specifically designed for spontaneously breathing patients. This device has not been investigated in vivo yet. It's known that using a spacer during nebulization improves aerosol delivery. We hypothetized that lung deposition could be highly increased with the Aeroneb Solo Adapter in comparison to a standard jet nebulizer.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Technetium-99m - Diethylenetriaminepentaacetic acid	Solution placed on the nebulizer reservoir
DEVICE	Aeroneb Solo Adapter	Nebulizer
DEVICE	Opti-Mist Plus Nebulizer	Standard jet nebulizer
OTHER	Planar scintigraphy	Imaging technique to investigate whole lung deposition
OTHER	Single photon emission computed tomography	Imaging technique to investigate regional pulmonary deposition
OTHER	Spirometry	FEV1, FVC assessment

Timeline

• Start date: 2014-09-01
• Primary completion: 2015-06-01
• First posted: 2014-11-21
• Last updated: 2015-11-17

Locations

1 site across 1 country: Belgium