NCT02295579

Will Lactobacillus Increase Cure Rate After Treatment of Bacterial Vaginosis and Chronic Vulvovaginal Candida

Vaginal Colonization After Treatment With Lactobacillus in Women With BV or Candida Will That Increase the Cure Rate After Treatment With Clindamycin for BV and Flucnazole for Candida

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Skaraborg Hospital · Other Government
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

From the earlier studies the investigators have treated women with bacterial vaginosis and cronic vulvovaginal candida. The investigators have then treated them with laktobacilli 10 days for 2 month. The investigators will continue to follow them and investigate if treatment with lactobacilli every week for 6 month will increase cure rate.

Detailed description

Clinical diagnosis of bacterial vaginosis using air dried smears combined with Hay/Ison classification. Test of cure every month or every menstrual cycle using self taken smears. The cure will be if the woman are in group 1 according to Hay/Ison classification. This will also allow us to use molecular diagnosis of BV to test cure and compare this with hay/Ison. Test of cure for candida patiens are no visibel candida on wet smear and free of symtoms of candida.

Conditions

• Bacterial Vaginosis

Interventions

Type	Name	Description
OTHER	lactobacillus (EcoVag)	Probiotic human lactobacillus (L. gasseri and L rahmnosus)

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-06-01
• Completion: 2015-11-01
• First posted: 2014-11-20
• Last updated: 2019-08-14

Locations

2 sites across 1 country: Sweden