NCT02293759

Trial of HoLEP vs. PVP in Treating BPH in Patients With Bleeding Tendency

Prospective Non-randomized Trial Comparing Holmium Laser Enucleation of the Prostate Versus Greenlight Laser Photoselective Vaporization of the Prostate in Treating Benign Prostate Hyperplasia in Patients With Bleeding Tendency

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: Male
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Patients presented for BPH surgery at our out patient clinic will be assessed for abnormal bleeding profile. Patients with bleeding tendency will be offered either HoLEP or Greenlight laser PVP based on prostate size cut off point of 80ml Larger prostates will be treated with HoLEP Smaller prostates will be treated with greenlight PVP

Detailed description

Elderly patients with bleeding tendency either secondary; 1. Strict antiplatelet intake 2. Strict anticoagulant intake 3. uncorrected natural bleeding tendency e.g; patients with liver cell failure are at higher risk of perioperative bleeding when subjected to prostate surgery. Laser prostate surery was introduced to overcome this difficulty. However, till now there is no head to head comparision of different types of laser procedures in treating this subset of patients In the current study patients presented for BPH surgery in a tertiarry referral prostate unit will be assessed for bleeding tendency and will be treated either by Holmium laser enucleatiuon of the prostate or Greenlight laser vaporization of the prostate Single surgeon will perform all cases

Conditions

• Benign Prostatic Hyperplasia

Interventions

Type	Name	Description
PROCEDURE	HoLEP	Holmium laser enucleation of the prsotate
PROCEDURE	Greenlight laser PVP	Greenlight laser (532nm) Photoslective vaporization of the prostate

Timeline

• Start date: 2014-10-01
• Primary completion: 2016-08-01
• Completion: 2016-09-01
• First posted: 2014-11-18
• Last updated: 2016-03-29

Locations

1 site across 1 country: Egypt