Clinical Trials Directory

Trials / Completed

CompletedNCT02291861

Addressing Involuntary Movements in Tardive Dyskinesia

A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose Study of SD-809 (Deutetrabenazine) for the Treatment of Moderate to Severe Tardive Dyskinesia

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
298 (actual)
Sponsor
Auspex Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether fixed-doses of an investigational drug, SD-809 (deutetrabenazine), will reduce the severity of abnormal involuntary movements of tardive dyskinesia.

Conditions

Interventions

TypeNameDescription
DRUGSD-809SD-809 tablets dose titrated for 4 weeks until target randomized dose is reached. The dose is maintained for an additional 8 weeks. Tablets were swallowed whole with water and taken with food.
DRUGPlaceboPlacebo tablets taken twice daily for 12 weeks. Tablets were swallowed whole with water and taken with food.

Timeline

Start date
2014-10-31
Primary completion
2016-08-19
Completion
2016-08-19
First posted
2014-11-17
Last updated
2021-11-09
Results posted
2018-04-11

Locations

106 sites across 6 countries: United States, Czechia, Germany, Hungary, Poland, Slovakia

Source: ClinicalTrials.gov record NCT02291861. Inclusion in this directory is not an endorsement.