NCT02290535

Electrical Impedance Tomography of Lung in Child and Young Age

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 192 (actual)
• Sponsor: RWTH Aachen University · Academic / Other
• Sex: All
• Age: 5 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The investigator will determine a compliance of two diagnostic techniques (EIT and Body plethysmography) in collective of children and teenagers with obstructive lung disease and a matched control group.

Detailed description

The aim of the present study is verification of the correlation between EIT-derived data and following extracted parameters of the pulmonary function: * forced expiratory volume in 1 second (FEV 1) * forced vital capacity (FVC) * relative forced expiratory volume in 1 second (FEV1/FVC) * maximal expiratory flow (MEF 25) * total lung capacity (TLC) * resistance (Raw). These findings could bring out new prospective opportunity for pulmonary function tests without cooperation. Furthermore, the study aims to clarify whether EIT technique can be used for regional pulmonary function testing. In addition, dynamic lung function parameter and static radiological techniques will be correlated with EIT.

Conditions

• Obstructive Lung Diseases

Interventions

Type	Name	Description
PROCEDURE	patients	The 16-electrode belt will be applied to patient's chest. Following vital signs will be recorded: respiratory rate at rest breathing, heart rate, transcutaneous oxygen saturation. Then impulse oscillometry (IOS) will be performed in a sitting position. After that, subjects with cooperation willingness will get a body plethysmography. A spirometry / forced breathing maneuvers will be performed. All patients will receive 2 strokes salbutamol inhaler for bronchospasmolysis. Please note that inhalation of salbutamol is not study related. It is used in the clinical routine to examine the reversibility of the bronchial obstruction in patients with obstructive lung disease in course of the lung function test. Ten minutes later measurements described above will be repeated.
PROCEDURE	probands	Probands will receive the same treatment as patients, but without bronchospasmolysis.

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-01-01
• Completion: 2015-01-01
• First posted: 2014-11-14
• Last updated: 2015-07-16

Locations

1 site across 1 country: Germany