NCT02290314

Midline Lumbar Fusion Versus Posterior Lumbar Interbody Fusion

Minimal Access Midline Lumbar Fusion Versus Traditional Open Posterior Lumbar Interbody Fusion for Degenerative Lumbar Spondylolisthesis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: The London Spine Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Degenerative lumbar spondylolisthesis is the forward displacement (slip) of one vertebra on an adjacent vertebra resulting in narrowing of the spinal canal or compression of the exiting nerve roots. It is commonly associated with low back and leg pain, and is a frequent reason for spine surgery particularly in individuals over age 65 years. Recently novel minimally invasive surgical techniques have heightened public and government interest by touting benefits of reduced approached-related morbidity which in turn leads to quicker recovery, shorter hospital stay, improved short-term clinical outcomes, and reduced health care cost. However, there is no randomized controlled trial evidence to describe the actual advantages and disadvantages associated with minimally invasive spinal fusion. This pilot study is a randomized control trial comparing minimally invasive MID-line Lumbar Fusion (MIDLF) to traditional "open" posterior lumbar interbody fusion (PLIF) with respect to length of stay, approach related morbidity, patient centered outcome measures, and cost-effectiveness in the treatment of degenerative lumbar spondylolisthesis.

Conditions

• Degenerative Lumbar Spondylolisthesis

Interventions

Type	Name	Description
PROCEDURE	minimally invasive MID-line Lumbar Fusion (MIDLF)
PROCEDURE	Posterior lumbar interbody fusion (PLIF)

Timeline

• Start date: 2014-12-01
• Primary completion: 2018-12-01
• Completion: 2019-12-01
• First posted: 2014-11-14
• Last updated: 2018-08-20

Locations

2 sites across 1 country: Canada