NCT02289235

Effects of Ginger on Nonalcoholic Fatty Liver Disease in T2DM

The Effects of Ginger on Biochemical Markers and Imaging Studies of Patients With Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease (NAFLD)

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Shiraz University of Medical Sciences · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The investigators want to evaluate the effects and safety of ginger in treatment of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM).

Detailed description

Ginger (Zingiber officinale Roscoe) has been cultivated for medicinal and culinary purposes for at least two millennia. It contains several hundred valuable compounds and new constituents are still being found. Ginger's high antioxidant value has proved highly effective with its ability to scavenge a number of free radicals and protect cell membrane lipids from oxidation in a dose-dependent manner. In a randomized double-blind placebo-controlled clinical trial, the investigators want to investigate the effects of ginger in treatment of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM).

Conditions

• Fatty Liver
• Diabetes Mellitus, Type 2

Interventions

Type	Name	Description
DRUG	Ginger	Ginger powder capsule 1000 mg twice daily for 3 months
DRUG	Placebo	Placebo powder 2 capsules twice daily for 3 months

Timeline

• Start date: 2019-05-01
• Primary completion: 2020-01-01
• Completion: 2020-02-01
• First posted: 2014-11-13
• Last updated: 2020-10-20

Locations

1 site across 1 country: Iran