Clinical Trials Directory

Trials / Completed

CompletedNCT02289196

Safety Study of Vx006 Vaccine in Solid Tumor Patients

A Multicenter, Open Label, Uncontrolled Phase I Trial to Compare Safety, Tolerability and Immunogenicity of Vx-006 Vaccine at 0.5mg, 1mg, 5mg and 10mg Doses in Human Leukocyte Antigen-A02 (HLA-A02) Positive Patients With Solid Tumours

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
23 (actual)
Sponsor
Vaxon Biotech · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Patients with histologically proven malignancy with documented disease control (objective response or stable disease) or Not Evaluable Disease (NED) expectancy \> 6 months; only HLA-A\*02 positive patients. The primary objective of the trial is to compare safety and tolerability of four different doses of Vx-006. The secondary objective is to compare immunogenicity of four different doses of the Vx-006.

Conditions

Interventions

TypeNameDescription
DRUGVx-006: 0,5mg
DRUGVx-006: 1mg
DRUGVx-006: 5mg
DRUGVx-006: 10mg

Timeline

Start date
2014-03-01
Primary completion
2014-10-01
Completion
2017-05-01
First posted
2014-11-13
Last updated
2019-06-19

Locations

3 sites across 1 country: Greece

Source: ClinicalTrials.gov record NCT02289196. Inclusion in this directory is not an endorsement.