Trials / Completed
CompletedNCT02289118
Tau Imaging in Young Onset Dementia
[18F]-T807 PET/CT Imaging of Tau Pathology in Young Onset Focal Dementia
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 16 (actual)
- Sponsor
- University of Pennsylvania · Academic / Other
- Sex
- All
- Age
- 45 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The central goal of this study is to determine and compare the similarities and differences in regional brain uptake of \[18F\]T807 in patients with typical Alzheimer's Disease (AD), Posterior Cortical Atrophy (PCA), and Logopenic Variant of Primary Progressive Aphasia (lvPPA). The investigators will correlate patterns of \[18F\]T807 binding with magnetic resonance imaging (MRI)-based regional volumetric and cortical thickness measures. If cerebral spinal fluid (CSF) samples are not available, patients may be asked to get an optional lumbar puncture (LP) for additional comparisons. The investigators will recruit 20 participants, 45-70 years old, with clinical evidence of young onset focal dementia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | [18F]-T807 imaging tracer | Tau Imaging tracer |
Timeline
- Start date
- 2014-11-01
- Primary completion
- 2018-12-01
- Completion
- 2019-01-31
- First posted
- 2014-11-13
- Last updated
- 2020-03-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02289118. Inclusion in this directory is not an endorsement.