Trials / Completed
CompletedNCT02287493
Pharmacokinetics of Selected Antiinfectives During Sustained Low-efficiency Dialysis (SLED)
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 35 (actual)
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
In a prospective, non-interventional, monocentric observational study the pharmacokinetic properties of selected antiinfective drugs during sustained low-efficiency dialysis (SLED) will be analyzed.
Detailed description
Antibiotic concentrations are measured whilst patients receive SLED for renal replacement therapy. The plasma specimens will be quantified using high Performance liquid chromatography (HPLC). Primary endpoint: \- Plasma levels of antiinfectives during SLED Secondary endpoints: * mortality * length of stay at the intensive care unit (ICU) and hospital * clinical cure of infections Inclusion criteria: * age: \> 18 years * patients under SLED * antiinfective treatment exclusion criteria: \- missing informed consent
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Pharmacokinetic Analysis |
Timeline
- Start date
- 2013-07-01
- Primary completion
- 2016-12-01
- Completion
- 2016-12-01
- First posted
- 2014-11-10
- Last updated
- 2021-12-14
- Results posted
- 2021-02-18
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02287493. Inclusion in this directory is not an endorsement.