NCT02284672

The Effect of Dexmedetomidine on Propofol Requirement for Insertion of Laryngeal Mask Airway

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 39 (actual)
• Sponsor: Ajou University School of Medicine · Academic / Other
• Sex: All
• Age: 19 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Propofol frequently used as an inducting medication for insertion Laryngeal mask airway(LMA). But propofol alone can be not sufficient for inhibiting upper airway reflex and also result in cardiovascular suppression under enough amount. Dexmedetomidine is a selective alplh2 receptor agonist with analgesic and sedative effects but sparing respiratory function. Therefore propofol combined with dexmedetomidine induction could be more effective in preserve respiration under same condition for LMA insertion than propofol alone. In this study, the investigators investigate the clinical dose of propofol for LMA insertion with premedication of dexmedetomidine, and evaluate the effect of dexmedetomidine.

Conditions

• Precedex Effect to Propofol Requirement

Interventions

Type	Name	Description
DRUG	Dexmedetomidine
DRUG	Normal saline

Timeline

• Start date: 2014-11-01
• Primary completion: 2016-01-01
• Completion: 2016-01-01
• First posted: 2014-11-06
• Last updated: 2016-02-29

Locations

1 site across 1 country: South Korea