Trials / Unknown
UnknownNCT02284048
Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular Angina
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 140 (estimated)
- Sponsor
- Second Xiangya Hospital of Central South University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This study is undertaken to determine if ticagrelor augments adenosine-induced coronary flow reserve (CFR), ameliorates clinical symptomatology and exercise tolerance in patients with MVA
Detailed description
Considering the reduced CFR and increased platelet aggregability in patients with MVA, together with the augmented effect on adenosine-mediated coronary blood flow and potent antiplatelet effect of ticagrelor, we speculate that ticagrelor can promisingly ameliorate the coronary microvascular function in patients with MVA.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ticagrelor | compare the effect of ticagrelor and control on the Coronary Flow Reserve in patients with microvessel angian |
Timeline
- Start date
- 2014-11-01
- Primary completion
- 2016-11-01
- Completion
- 2017-11-01
- First posted
- 2014-11-05
- Last updated
- 2014-11-06
Source: ClinicalTrials.gov record NCT02284048. Inclusion in this directory is not an endorsement.