Clinical Trials Directory

Trials / Completed

CompletedNCT02280629

Phosphatidylcholine (LT-02) vs. Placebo vs. Mesalamine for Maintenance of Remission in Ulcerative Colitis (PROTECT-2)

Randomized, Double-blind, Double-dummy, Placebo-controlled, Phase III Clinical Trial on the Efficacy and Safety of a 48-weeks Treatment With Gastro-resistant Phosphatidylcholine (LT-02) Versus Placebo Versus Mesalamine for Maintenance of Remission in Patients With Ulcerative Colitis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
150 (actual)
Sponsor
Dr. Falk Pharma GmbH · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to prove the superiority of a 48-weeks treatment with 3.2 g/day delayed-release phosphatidylcholine (LT-02) versus placebo for the maintenance of remission in patients with ulcerative colitis (UC)

Conditions

Interventions

TypeNameDescription
DRUGLT-02LT-02 1.6g twice daily AND mesalamine PLACEBO three-times daily
DRUGPlaceboLT-02 PLACEBO twice daily AND mesalamine PLACEBO three-times daily
DRUGMesalamineLT-02 PLACEBO twice daily AND mesalamine 500mg three-times daily

Timeline

Start date
2014-10-01
Primary completion
2018-10-05
Completion
2018-10-05
First posted
2014-10-31
Last updated
2020-01-27

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT02280629. Inclusion in this directory is not an endorsement.