Clinical Trials Directory

Trials / Completed

CompletedNCT02275364

Functional Magnetic Resonance Imaging (fMRI) Study of Nasal Strips in Nasal Congestion

A Magnetic Resonance Imaging Study of Nasal Strips in Subjects With Nasal Congestion

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
28 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The aim of the study is to evaluate the effect of the nasal strip (relative to the placebo strip) on the nasal passages using anatomical MRI scans and to demonstrate the effect of the strip on breathing correlated cortical activity, using interoceptive fMRI task and analysis techniques derived from physiological data collected during scanning.

Conditions

Interventions

TypeNameDescription
DEVICETest stripClass I device for the application to the nose to facilitate better air flow through the nose
DEVICEPlacebo stripPlacebo strip
OTHERNasal sprayNasal decongestant to be used on a single occasion (one spray per nostril), 20 minutes prior to commencing the third MRI scanning sessions.

Timeline

Start date
2013-08-05
Primary completion
2013-10-30
Completion
2013-10-30
First posted
2014-10-27
Last updated
2017-08-02
Results posted
2015-01-26

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT02275364. Inclusion in this directory is not an endorsement.