NCT02275247

Perioperative Neuroprotection of Stellate Ganglion Block

Preventive Effect of Stellate Ganglion Block on Cerebral Vasospasm in Patients Undergoing Aneurysm Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: General Hospital of Ningxia Medical University · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

To investigate whether stellate ganglion block is helpful to brain protection during cranial aneurysm surgery

Detailed description

The vasospasm after cranial aneurysm surgery have a higher incidence, but not have an ideal treatment method. At present, the medical treatment is very limited effect to prevent the perioperative cerebral ischemia.Stellate ganglion block （SGB）is an effective and well-tolerated approach to the treatment of CVS in various clinical settings.Resent study indicated that SGB has a protective effect on delayed cerebral vasospasm in an experimental rat model of subarachnoid hemorrhage.Therefore,we hypothesized that the preoperative SGB would be a effective treatment for improvement of vasospasm after cranial aneurysm surgery.

Conditions

• Intracranial Aneurysm

Interventions

Type	Name	Description
DRUG	Stellate Ganglion Block	stellate ganglion block will be administered using either 6-8mL saline (Group 1) or 0.25% ropivacaine 6-8mL (Group 2)

Timeline

• Start date: 2014-08-01
• Primary completion: 2015-10-01
• Completion: 2016-10-01
• First posted: 2014-10-27
• Last updated: 2016-05-20

Locations

1 site across 1 country: China