Clinical Trials Directory

Trials / Completed

CompletedNCT02267525

The Diabetic and Idiopathic Gastroparesis Efficacy, Safety, and Tolerability (DIGEST) Study

A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Phase 2 Study to Assess the Efficacy, Safety, and Tolerability of Velusetrag for the Treatment of Diabetic or Idiopathic Gastroparesis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
233 (actual)
Sponsor
Theravance Biopharma · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Study 0099 explores the efficacy and safety of multiple doses of velusetrag in the treatment of symptoms in subjects with diabetic or idiopathic gastroparesis. Three dose levels of velusetrag will be evaluated and compared to placebo for approximately 12 weeks of therapy. In addition, the study will be used to evaluate the psychometric properties of the Gastroparesis Rating Scale (GRS), a daily patient-reported outcome (PRO) measure.

Conditions

Interventions

TypeNameDescription
DRUGVelusetrag
DRUGPlacebo

Timeline

Start date
2014-12-01
Primary completion
2017-06-01
Completion
2017-06-01
First posted
2014-10-17
Last updated
2018-04-17

Source: ClinicalTrials.gov record NCT02267525. Inclusion in this directory is not an endorsement.

The Diabetic and Idiopathic Gastroparesis Efficacy, Safety, and Tolerability (DIGEST) Study (NCT02267525) · Clinical Trials Directory