Trials / Completed
CompletedNCT02267200
The Screening and Analysis of Plasma Biomarkers in Irreversible PAH-CHD
The Screening and Analysis of Plasma Biomarkers in Irreversible Pulmonary Arterial Hypertension Associated With Congenital Heart Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (actual)
- Sponsor
- Shanghai Jiao Tong University School of Medicine · Academic / Other
- Sex
- All
- Age
- 1 Month – 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to analyse the sensitivity and specificity of circulating endothelial cells to predict irreversible pulmonary arterial hypertension associated with congenital heart disease.
Detailed description
predict to recruit 100 patients with pulmonary arterial hypertension (PAH)associated with CHD，under the commitment of the children's parents，take 3-4ml central venous blood before the corrective surgery，then calculate the number of the circulating endothelial cells by flow cytometer AND detect the expression of micro RNAs to screen out the biomarker，through the 6 months follow-up, separated the reversible and irreversible PAH,then to carry on the statistics.
Conditions
Timeline
- Start date
- 2014-10-01
- Primary completion
- 2016-09-01
- Completion
- 2016-09-01
- First posted
- 2014-10-17
- Last updated
- 2016-11-22
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02267200. Inclusion in this directory is not an endorsement.