NCT02264587

Effects and Mechanism of Mosapride Citrate on Diabetic Gastroparesis

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Liangzhou Wei · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effects and mechanism of mosapride citrate on diabetic gastroparesi.

Detailed description

To evaluate the effect of mosapride on DPG by 13 C - octylic acid breath test. IF C13- octylic acid be absorbed by mucous membrane of small intestine, octylic acid will be oxidated to CO2.Patients eating food containing C13, and then collect their expired gas at 15, 30,45,60,75,90,105,120,150,180,210,240min, analyse the mass of C13 by mass spectrometer, then can calculate the gastric emptying rate.

Conditions

• Diabetic Gastroparesis

Interventions

Type	Name	Description
DRUG	Mosapride	Mosapride 5mg by mouth ,3 times one day for 1 4days.
DRUG	domperidone	Domperidone 10mg by mouth ,3 times one day for 1 4days.

Timeline

• Start date: 2014-10-01
• Primary completion: 2015-09-01
• Completion: 2015-12-01
• First posted: 2014-10-15
• Last updated: 2014-10-15