NCT02264509

Peripheral Arterial Insufficiency Associated With HIV/AIDS

Prevalence and Risk Factors of Arterial Insufficiency in Patients With HIV / AIDS

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 206 (actual)
• Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the risk factors associated with the occurrence of arterial insufficiency in patients with HIV / AIDS, and to identify the prevalence of this disease. The estimated prevalence is 10%, similar to that reported in the general population.

Detailed description

A case study nested in a cohort of patients with HIV / AIDS at Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, with a cohort of 1500 patients , a sample size of 206 individuals was calculated. Data collection was performed in a prospective cross shape. During the interview, written informed consent for inclusion in the study, along with a standard query of vascular surgery in which the patient's history as well as cardiovascular risk factors. Also, a vascular physical examination including palpation of pulses in upper and lower extremities (brachial, radial, ulnar, femoral, popliteal, posterior tibial and dorsalis pedis), femoral murmurs search and determining ankle / brachial indexes with a standardized method. In determining the ABI was counted with a Doppler ultrasound 8 mHz, transducer gel and a sleeve for manual measurement of blood pressure, 20% longer than the largest diameter of the arm circumference. If the patient is diagnosed with, symptomatic or asymptomatic arterial insufficiency, ABI measurements were performed at rest and effort, plus pressure index finger-arm or plethysmography. Patients with altered rates were followed in vascular surgery care. The data were recorded in a single database unique protected by password. The results were analyzed using the statistical program STATA v 9.0.

Conditions

• Arterial Insufficiency
• Acquired Immunodeficiency Syndrome
• HIV

Interventions

Type	Name	Description
PROCEDURE	Ankle-Brachial index	The only procedure to be performed is the measurement of ABI for the diagnosis of arterial insufficiency.

Timeline

• Start date: 2014-09-01
• Primary completion: 2014-11-01
• Completion: 2014-12-01
• First posted: 2014-10-15
• Last updated: 2016-01-29

Locations

1 site across 1 country: Mexico