Clinical Trials Directory

Trials / Completed

CompletedNCT02263456

A Study to Compare the Pharmacokinetics and Safety of Replenine®-VF, Replenine® or Other Factor IX in Haemophilia B

An Open Study to Compare the Pharmacokinetics and Safety of Replenine®-VF and Replenine® or Any Other High Purity Factor IX Concentrate, in Severe Haemophilia B Patients.

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
Sponsor
Bio Products Laboratory · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is: * to compare the pharmacokinetics of Replenine®-VF and Replenine® or any other high purity Factor IX concentrate, when given as a bolus dose of 75IU/kg. * to compare the 1st and 2nd pharmacokinetic assessments on Replenine®-VF (conducted 3 months apart) and recovery if patients changes batches. * to evaluate Replenine®-VF in terms of clinical tolerance and safety in patients with severe haemophilia B.

Conditions

Interventions

TypeNameDescription
BIOLOGICALReplenine®-VF (High Purity Factor IX)

Timeline

Start date
1997-07-01
Primary completion
2001-09-01
First posted
2014-10-13
Last updated
2014-10-13

Locations

7 sites across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT02263456. Inclusion in this directory is not an endorsement.