Trials / Unknown
UnknownNCT02260375
MSC Therapy in Liver Transplantation
THIRD-PARTY BONE MARROW-DERIVED MESENCHYMAL STROMAL CELLS TO INDUCE TOLERANCE IN LIVER TRANSPLANT RECIPIENTS
- Status
- Unknown
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- Monia Lorini · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The general aim of the present study is to test a cell therapy with third-party allogeneic ex-vivo expanded MSCs as a strategy to induce tolerance in liver transplant recipients. MSCs will be prepared accordingly to established protocols , starting from diagnostic samples of bone marrow aspirates (2-5 mL) or using the remnants in the bag and filter at the end of the bone marrow infusions. From these samples, MSCs will be expanded in GMP approved facilities and used for the present study in patients undergoing liver transplantation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Mesenchymal Stromal Cells |
Timeline
- Start date
- 2014-10-01
- Primary completion
- 2024-10-01
- Completion
- 2025-10-01
- First posted
- 2014-10-09
- Last updated
- 2018-04-06
Locations
6 sites across 1 country: Italy
Source: ClinicalTrials.gov record NCT02260375. Inclusion in this directory is not an endorsement.