NCT02260206

Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion

Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Following Catheter Ablation of Atrial Fibrillation

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Yong Seog Oh · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.

Detailed description

RFCA was started as a rhythm control of atrial fibrillation about 10 years before and the superiority of RFCA to medical treatment has been continuously reporting, so RFCA is globally performed nowadays. Acute pericardial effusion could occur during RFCA as complication, that might be developed to cardiac tamponade needed immediate pericardiocentesis. The inflammation developed after pericardiocentesis might be associated with the recurrences of atrial fibrillation, it could be presumed by the frequent occurrence of atrial fibrillation after open-heart surgery. The inflammation can be suppressed by administration of colchicine and the effects of colchicine have been proven to decrease the development of atrial fibrillation.

Conditions

• Pericardial Effusion

Interventions

Type	Name	Description
DRUG	Colchicine	Impact of Colchicine therapy on arrhythmia Recurrence after Acute Pericardial Effusion following Catheter Ablation of Atrial Fibrillation

Timeline

• Start date: 2014-07-01
• Primary completion: 2019-09-01
• Completion: 2023-10-01
• First posted: 2014-10-09
• Last updated: 2024-04-23

Locations

1 site across 1 country: South Korea