NCT02259049

The Effects of L-Tyrosine on 24 Hour Blood Pressure and Heart Rate in Parkinson's Disease

The Effects of L-Tyrosine on Non-invasive Ambulatory Blood Pressure and Heart Rate Monitoring in Parkinson's Disease

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: New York Institute of Technology · Academic / Other
• Sex: All
• Age: 40 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

The investigators are observing the effects 2,000 mg of L-tyrosine will have on 24 hour blood pressure fluctuations in individuals with Parkinson's disease.

Detailed description

We will be monitoring 24 hour ambulatory BP and HR in subjects with PD on 3 separate visits. The first visit will be without an intervention to establish a baseline of 24 hour BP fluctuations. One week later the subject will be given either L-tyrosine (2,000 mg) with B6 (10 mg) or a sugar pill. We will monitor 24 hour BP and HR after supplementation. One week later the subject will repeat the same procedures with either supplement or placebo. This is a total of 3 visits with 24 hour ambulatory BP and HR monitoring.

Conditions

• Blood Pressure

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	L-tyrosine	Each subject will receive 2,000 mg of L-tyrosine BID for 24 hours.
DIETARY_SUPPLEMENT	Sugar Pill	Each subject will receive a sugar pill BID for 24 hours.

Timeline

• Start date: 2014-10-01
• Primary completion: 2015-09-01
• Completion: 2015-09-01
• First posted: 2014-10-08
• Last updated: 2016-01-20

Locations

1 site across 1 country: United States