Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT02257788

PRO 140 for Human Immunodeficiency Virus Infection

PRO 140 2103: A Phase 2a, Randomized Study of PRO 140 by Subcutaneous Injection in Adult Subjects With Human Immunodeficiency Virus Type 1 Infection

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Drexel University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

PRO 140 2103 is a multicenter, randomized parallel group study, conducted in male and female adult subjects infected with CCR5-tropic HIV-1.

Detailed description

Protocol PRO 140 2103 is a multicenter, randomized parallel group study, conducted in approximately 40 male and female adult subjects (n=10/treatment group) infected with CCR5-tropic HIV-1. Subjects will be randomized into one of four treatment groups. Blood samples for drug concentrations, PD variables, and efficacy variables will be obtained over a 59-day period following initiation of dosing. Safety will be monitored throughout the course of the study.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPRO 140Humanized monoclonal antibody to CCR5

Timeline

Start date
2014-09-01
Primary completion
2015-02-01
Completion
2015-02-01
First posted
2014-10-06
Last updated
2017-03-09

Locations

7 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02257788. Inclusion in this directory is not an endorsement.