NCT02256163

Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm

Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm (TAA)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 258 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objectives of the study are * to assess the contribution of alteration of each known gene on non-syndromic TAA. * to map and identify unknown gene involved in the non-syndromic TAA.

Detailed description

The secondary objectives of the study are * to study the correlation of phenotype-genotype, in particular, to compare the aortic phenotype of non-syndromic TAA patients and TAA syndromic patients. * to develop national standardized strategies of genetic diagnosis and of clinical management using genetic data.

Conditions

• Thoracic Aortic Aneurysm

Timeline

• Start date: 2011-06-01
• Primary completion: 2016-12-01
• Completion: 2017-03-01
• First posted: 2014-10-03
• Last updated: 2017-11-20

Locations

1 site across 1 country: France