NCT02255149

A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw

Vertical Ridge Augmentation Using Titanium Mesh and Allograft in Posterior Mandible: A Feasibility Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed. Implants will be placed in the newly formed bone. The goal of this study is to test how well using a newly designed titanium mesh and bone particles can grow bone in the back of the lower jaw. The investigators are also checking if the newly formed bone will stay around implants that will have been in use for 12 months.

Detailed description

Inclusion Criteria * Patients are at least 18 years old * At least two adjacent back teeth in the lower jaw are missing * No medical contraindication to dental surgery * Inadequate vertical ridge height at edentulous region (less than 10mm) Exclusion Criteria * Unstable systemic diseases or conditions that would compromise the healing potential * Patients with osseous metabolic disorders (e.g., osteoporosis, Paget's disease etc.) * Patients who are pregnant or expect to get pregnant * Patients with unstable dental disease (e.g. caries and periodontitis) in the surgical sextant

Conditions

• Alveolar Bone Loss

Interventions

Type	Name	Description
DEVICE	Bone/Mesh	A titanium mesh (Ti-Mesh) that is more porous than other materials will be placed in order to hold a spot for the bone particles to grow.

Timeline

• Start date: 2011-09-01
• Primary completion: 2014-11-01
• Completion: 2014-11-01
• First posted: 2014-10-02
• Last updated: 2023-11-21
• Results posted: 2016-04-19