NCT02253381

Effect of Position During Spinal Anesthesia on Hemodynamic Change in Cesarean Section

Effect of Position During Spinal Anesthesia on Hemodynamic Change in Pregnant Women Undergoing Cesarean Section: Randomized Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: Prince of Songkla University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic. For right lateral decubitus, the enlarged uterus compresses inferior vena cava that may decrease venous return and cardiac output. This leads to hypotension.The hypothesis is the right lateral position during spinal anesthesia in pregnant women will be had hemodynamic changing more than the left lateral position. This objective is to compare hemodynamic change between left and right lateral position during spinal anesthesia in pregnant women undergoing cesarean section.

Detailed description

Study design: A randomized controlled trial Study setting: The study will be conducted in the operating rooms at Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand Study period: The total duration of participation in the randomized study is up to the operative day. Study population: Pregnant patients undergoing cesarean section receiving spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml. Study sample: Inclusion criteria 1. Signed informed consent 2. Pregnancy 3. Spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml 4. Elective and emergency surgery Exclusion criteria 1. Contraindication for spinal anesthesia 2. Complicated pregnancy such as maternal heart disease, eclampsia, severe fetal distress, abruption placenta, twin pregnancy, and placenta previa totalis 3. Maternal height \< 150 cm.

Conditions

• Hypotension

Interventions

Type	Name	Description
PROCEDURE	Right	Right lateral decubitus position during spinal anesthesia
PROCEDURE	Left	Left lateral decubitus position during spinal anesthesia

Timeline

• Start date: 2014-10-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2014-10-01
• Last updated: 2015-04-29

Locations

1 site across 1 country: Thailand