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CompletedNCT02249988

Clinical Efficacy of ABX203 Therapeutic Vaccine in HBeAg Negative Patients With Chronic Hepatitis B

Phase IIB-III Efficacy Study of ABX203 Vaccine as an Adjunct Therapy to Nucleos(t)Ide Analogs to Maintain Control of HBV Replication After Cessation of Treatment in HBeAg Negative Patients With Chronic Hepatitis B

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
261 (actual)
Sponsor
Abivax S.A. · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The study is an open-label, randomized, comparative, multicenter clinical trial. The purpose of this study is to assess the efficacy of ABX203, a new chronic hepatitis B therapeutic vaccine administered as an adjunct therapy to nucleos(t)ide analogs (NUCs), in maintaining control of Hepatitis B disease after cessation of treatment with NUCs in subjects with HBeAg negative chronic Hepatitis B.

Conditions

Interventions

TypeNameDescription
DRUGABX203 therapeutic Hepatitis B vaccine treatment arm

Timeline

Start date
2014-12-01
Primary completion
2016-12-01
Completion
2016-12-01
First posted
2014-09-26
Last updated
2017-01-24

Locations

12 sites across 2 countries: Australia, New Zealand

Source: ClinicalTrials.gov record NCT02249988. Inclusion in this directory is not an endorsement.

Clinical Efficacy of ABX203 Therapeutic Vaccine in HBeAg Negative Patients With Chronic Hepatitis B (NCT02249988) · Clinical Trials Directory