NCT02248753

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department (RACE 7 ACWAS-trial)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 437 (actual)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A symptomatic episode of the heart rhythm disorder 'atrial fibrillation' (AF) is a frequent reason for visits to the emergency department. Currently, in the majority of cases, immediate (electrical or pharmacological) cardioversion is chosen, while atrial fibrillation terminates spontaneously in 70% of the cases within 24 hours. A wait-and-see approach with rate-control medication only, and when needed cardioversion within 48 hours of onset of symptoms, could be effective, safe and more cost-effective than current standard of care and could lead to a higher quality of life.

Conditions

• Atrial Fibrillation

Interventions

Type	Name	Description
DRUG	Pharmacological cardioversion - Flecainide
PROCEDURE	Electrical cardioversion
DRUG	Metoprolol
DRUG	Verapamil
DRUG	Digoxin
DRUG	Pharmacological cardioversion - Amiodarone

Timeline

• Start date: 2014-10-01
• Primary completion: 2018-11-01
• Completion: 2019-12-01
• First posted: 2014-09-25
• Last updated: 2020-01-21

Locations

15 sites across 1 country: Netherlands