NCT02248337

Low Volume Colon Preparation for IBD

Colon Cleasing for Colonoscopy in Patients With IBD Colitis: Efficacy and Acceptability of 4 Liter PEG vs 2 Liter PEG Plus Bisacodil

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 216 (actual)
• Sponsor: Luigi Sacco University Hospital · Academic / Other
• Sex: —
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Comparison of two PEG-based bowel cleansing regimens in patients with inflammatory bowel disease.

Detailed description

Low-volume preparations are gaining attention for higher acceptability. This study compares efficacy, safety and tolerability of a 2L PEG solution plus bisacodil with a 4L PEG solution in patients with inflammatory bowel disease-related colitis. This will be a multicenter, randomized, single-blind study. Adult outpatients with IBD colitis undergoing colonoscopy will receive either 2L PEG plus biscodil or 4L PEG. Bowel cleansing will be assessed using the Ottawa Scale and rated as adequate if \<6. Patient acceptance, satisfaction, and related symptoms will be also recorded. The study will also focus on the factors affecting quality of preparation in inflammatory bowel disease patients such as disease characteristics and administration regimen

Conditions

• Inflammatory Bowel Disease

Interventions

Type	Name	Description
DRUG	Colon preparation for colonoscopy	Colon cleansing prior to perform colonoscopy

Timeline

• Start date: 2013-03-01
• Primary completion: 2013-12-01
• Completion: 2014-03-01
• First posted: 2014-09-25
• Last updated: 2014-09-25

Locations

1 site across 1 country: Italy