NCT02242591

Effect of Adductor Canal Block vs. Placebo on Muscle Strength, Mobilisation and Pain After Total Knee Arthroplasty

Effect of Adductor Canal Block vs. Placebo on Muscle Strength, Mobilisation and Pain on the First Post-operative Day After Total Knee Arthroplasty

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Ulrik Grevstad · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effect of adductor canal block (ACB) vs. placebo on muscle strength, mobility and pain on the first postoperative day after total knee alloplastic (TKA).

Detailed description

Patients will be included on the first day after TKA surgery and randomized in two groups. Each group will receive 2 ACB with a 1 hour interval, one ACB with an active drug, Ropivacaine, and another ACB with a placebo drug, Saline. At T0, arm ACB\_active/placebo will receive the active ACB with Ropivacaine followed by the placebo ACB at T60 (60 minutes after T0). At T0, arm ACB\_placebo/active will receive the placebo ACB with Saline followed by the active ACB with Ropivacaine at T60 (60 minutes after T0). Outcome measurements will be made at T60, 1 hour after the first ACB, and the difference in outcome between the groups will be compared. Baseline values will be measured prior to the first ACB. Final measurements at T120 (120 minutes after the initial ACB), will determine if the differences between the groups are eliminated, since both groups then have received an active ACB.

Conditions

• Knee Replacement Arthroplasty

Interventions

Type	Name	Description
DRUG	Ropivacaine 7,5 mg/ml
DRUG	Saline

Timeline

• Start date: 2014-08-01
• Primary completion: 2014-11-01
• Completion: 2014-11-01
• First posted: 2014-09-17
• Last updated: 2014-12-02

Locations

1 site across 1 country: Denmark