NCT02242058

QST-Pupillometry in Sickle Cell Disease Patients

Quantitative Sensory Testing and Pupillometry in Sickle Cell Disease Patients.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 96 (actual)
• Sponsor: Julia Finkel · Academic / Other
• Sex: All
• Age: 13 Years – 30 Years
• Healthy volunteers: Accepted

Summary

There has been little progress for effective treatment of pain in sickle cell disease (SCD) patients. Many organizations have recognized that understanding the causes and reducing the burden of pain in SCD is critical in order to improve the quality of life in SCD patients. As patients with SCD face the challenge of living with both acute and chronic pain which is often improperly treated, our translational and interdisciplinary project aims to identify objective measures of pain sensitivity and its biochemical and genetic correlates. We hypothesize that SCD patients will have decreased tolerance to thermal and electrical stimuli.

Conditions

• SCD With Severe Phenotype (HbSS, HbSβ0 Thalassemia, HbSOARab)

Interventions

Type	Name	Description
OTHER	Quantitative sensory testing

Timeline

• Start date: 2013-08-01
• Primary completion: 2018-11-01
• Completion: 2018-11-01
• First posted: 2014-09-16
• Last updated: 2020-01-21

Locations

2 sites across 1 country: United States