Trials / Terminated
TerminatedNCT02241096
PK Intravenous Lidocaine Infusion
Pharmacokinetics of Intravenous Lidocaine Infusion in Children
- Status
- Terminated
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 2 (actual)
- Sponsor
- Children's Hospital Medical Center, Cincinnati · Academic / Other
- Sex
- All
- Age
- 3 Years – 15 Years
- Healthy volunteers
- Not accepted
Summary
To determine safe concentration level of lidocaine infusion in children.
Detailed description
This study will address the working hypothesis that intravenous lidocaine may be administered as a bolus followed by an infusion with reliable and safe blood levels of lidocaine. Serial blood draws will be obtained to determine safety of lidocaine doses used in this study by measuring blood levels of lidocaine and its metabolites.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Lidocaine | IV lidocaine bolus of 1.5mg/kg over 10 minutes followed by a 1mg/kg/hr IV lidocaine infusion. |
Timeline
- Start date
- 2015-01-01
- Primary completion
- 2015-09-01
- Completion
- 2015-09-01
- First posted
- 2014-09-16
- Last updated
- 2020-03-02
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02241096. Inclusion in this directory is not an endorsement.