NCT02239029

Platelet Rich Plasma on Osteoarthritis of Knee

The Effect of Platelet Rich Plasma on Osteoarthritis of Knee

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Yung-Tsan Wu · Academic / Other
• Sex: All
• Age: 35 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Although few studies have showed beneficial effect of platelet rich plasma (PRP) for osteoarthritis of knee (OA knee), only one study applied randomized, control method and none of them has the objective measurements such as balance test or muscle strength which were reported as decrease in patients with OA knees. We assess the analgesic effect and the extent of improved muscle strength and balance after PRP in patients with OA knee.

Detailed description

Patients with bilateral OA knee will be enrolled and randomized into intervention and control knee. One dose of PRP is applied in the intervention knee and normal saline in control side. Outcome measurements included visual analog scale (VAS)、Lequesne's severity index、Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)、balance test (Biodex) and isokinetic strengthening test at different follow-up frame (2nd week, 1st month, 3rd month and 6th month after treatment).

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	platelet rich plasma	Platelet rich plasma (PRP) is a new and potential treatment for patients with kinds of musculoskeletal disorders.
DRUG	Normal saline	The normal salin as the placebo intervention was injection in the other side of knee.

Timeline

• Start date: 2014-08-01
• Primary completion: 2016-10-01
• Completion: 2016-10-01
• First posted: 2014-09-12
• Last updated: 2016-12-06

Locations

1 site across 1 country: Taiwan