Trials / Active Not Recruiting
Active Not RecruitingNCT02238990
Biomarkerscreening in Cervical Cancer and Its Preinvasive Lesions
Biomarkerscreening Via Transcriptome and Methylosome Analysis in Cervical Cancer and Its Preinvasive Lesions
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- University of Luebeck · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Accepted
Summary
The following trial is a multicenter and prospective research trial of the colposcopy unit of luebeck university and the national research center in Borstel, Germany. The study is to identify and evaluate new biomarkers in human papilloma virus (HPV) associated malignancies and its preinvasive lesions of the cervix uteri. Fresh tissue samples being removed during conizations and/or hysterectomies are to be fixed in HOPE's solution and analyzed according to their transcriptomes and methylosome. The hereby found candidates are to be validated using immunohistochemistry and RT \[real-time\] -PCR \[polymerase chain reaction\]. The project is meant to be followed by continuous studies developing a new test describing the malignant potential of HPV associated genital lesions.
Conditions
Timeline
- Start date
- 2014-09-01
- Primary completion
- 2030-12-01
- Completion
- 2030-12-01
- First posted
- 2014-09-12
- Last updated
- 2022-05-31
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02238990. Inclusion in this directory is not an endorsement.