NCT02238379

Intranasal Oxytocin Administration and the Neural Correlates of Social and Non-Social Visual Perception

Oxytocin Pilot: Oxytocin and Face Perception

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: Female
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to investigate the effects of oxytocin on social behavior and brain activity using EEG and the event-related potential (ERP) technique. The value of EEG is its high temporal specificity, enabling precision in the timing of social behavior to be addressed. In order to elicit social responses in the human brain, a variety of social and emotional visual stimuli will be presented during EEG recording, namely infant and adult faces and houses. Brain responses after intranasal oxytocin will then be compared with placebo, to examine the effect of intranasal oxytocin on central nervous system activity. We hypothesize that intranasal oxytocin will enhance the neural response to social stimuli (infant and adult faces) but not to non-social stimuli (houses).

Conditions

• Social Perception

Interventions

Type	Name	Description
DRUG	Oxytocin	24 International Units of Oxytocin in a Nasal Spray
OTHER	Placebo	Placebo will contain all ingredients except the active oxytocin in the Nasal Spray.

Timeline

• Start date: 2014-09-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2014-09-12
• Last updated: 2018-01-17
• Results posted: 2017-05-25

Locations

1 site across 1 country: United States