NCT02238028

Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators

Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators: a Randomized Controlled Crossover Trial Among Healthy Young Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.

Detailed description

A group of healthy adult college students fulfilling the recruitment criteria were randomly divided into two sub-groups. One sub-group weared the particulate filtering respirators for 2 continuous days during which the respirator was required to wear as much as possible both indoor and outdoor. The other group acted as normal at the same time. The measurements on health effects including heart rate varibility, blood pressure, circulating biomarkers as well as the ambient air pollution were performed in both groups during the intervention period. After a 3-week rest period,the two groups interchanged their roles of wearing the respirator or not. The same measurements of both health effects indicators and ambient air pollution were repeated.

Conditions

• Autonomic Nervous System Imbalance
• Blood Pressure
• Inflammation
• Vasoconstriction
• Blood Coagulation Disorders

Interventions

Type	Name	Description
BEHAVIORAL	Wear respirator	Healthy adult subjects wore the particulate filtering respirators for continuous 48 hours as much as possible both indoor and outdoor.

Timeline

• Start date: 2014-03-01
• Primary completion: 2014-10-01
• Completion: 2014-12-01
• First posted: 2014-09-12
• Last updated: 2016-05-06
• Results posted: 2016-05-06

Locations

1 site across 1 country: China