Trials / Completed
CompletedNCT02236897
PET Imaging in ALS Patients
Metabotropic Glutamate Receptor 5 (mGluR5) Imaging in Amyotrophic Lateral Sclerosis (ALS) Patients and Healthy Volunteers
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 36 (actual)
- Sponsor
- Johns Hopkins University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
This is a pilot study to evaluate a potential imaging biomarker for aiding diagnosis and monitoring progression of ALS, based on a well established basic science pathway, published human autopsy data, preliminary data in ALS mutant mice, and our recently published data using brain PET scans to image the metabotropic glutamate receptor type 5 (mGluR5) in healthy human volunteers.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | PET Scanning |
Timeline
- Start date
- 2013-08-01
- Primary completion
- 2017-03-01
- Completion
- 2017-03-01
- First posted
- 2014-09-11
- Last updated
- 2017-03-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02236897. Inclusion in this directory is not an endorsement.