NCT02236429

Vaginal Flora for Treatment of Bacterial Vaginosis

Vaginal Flora Transplantation for Recurrent Bacterial Vaginosis

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Hadassah Medical Organization · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Bacterial vaginosis (BV) is the most common vaginal infection in women. It is caused by a vaginal bacterial imbalance. Treatment with antibiotics is the standard of care but there is a high rate of recurrence. Almost half of women successfully treated suffer a recurrence within three months. Complications include risk factors for premature birth, increased transmission of sexually transmitted diseases and higher risk for carcinoma of cervix. The investigators proposed study is a cost effective treatment based on returning the normal microbial balance to the vagina. The investigators propose to transfer normal vaginal flora from healthy individuals to women with BV and thus restore normal vaginal flora and cure this disorder.

Conditions

• Recurrent Bacterial Vaginitis

Interventions

Type	Name	Description
BIOLOGICAL	vaginal flora transplant

Timeline

• Start date: 2015-06-01
• Primary completion: 2026-03-01
• Completion: 2026-03-01
• First posted: 2014-09-10
• Last updated: 2025-09-24

Locations

1 site across 1 country: Israel