NCT02226809

Multi-center Study of Residual Neuromuscular Block Incidence in the Post-anesthesia Care Unit

Incidence of Residual Neuromuscular Block in Adult Patients in the Postanesthesia Care Unit. An Observational Cross-sectional Study of a Multicenter Cohort. The Residual Curarization in Spain Study (ReCuSS).

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 763 (actual)
• Sponsor: University of Valencia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Residual neuromuscular block (RNMB) is frequent in the immediate postoperative period and is a source of complications, mainly respiratory. The incidence is variable due to multiple factors. In Spain the incidence is unknown. The investigators hypothesize that a number of patients in the postanesthesia care unit (PACU) present with RNMB after general anesthesia using intermediate action neuromuscular block agents (NMBA). The main objective is to know the incidence of RNMB in Spanish hospitals. Secondary objectives are to observe the possible relationship with other pre- and intraoperative factors.

Detailed description

Residual neuromuscular block (RNMB) is frequent in the immediate postoperative period and is a source of complications, mainly respiratory. This includes recovery delay or hospital discharge delays, respiratory insufficiency or infections, unforeseen ICU admissions, and prolonged ICU stays. The incidence is variable due to multiple factors. Age, gender, surgery, NMBA type and doses, temperature, medications, etc. In several studies it has been found and incidence between 6-80%. Few studies have been focused in evaluating the incidence in the whole country, as representing a global anesthesia practice. In Spain the incidence is unknown. The investigators hypothesize that a number of patients in the postanesthesia care unit (PACU) present with RNMB after general anesthesia using intermediate action NMBA. The main objective is to know the incidence of RNMB in Spanish hospitals, by means of an observational cross-sectional multicenter study . Secondary objectives are to observe the possible relationship with other pre- and intraoperative factors.

Conditions

• Incomplete Reversal of Neuromuscular Block
• Postoperative Respiratory Complications

Interventions

Type	Name	Description
DEVICE	Accelerometry	Application of TOF stimulus (40 mA, three to four times) and recording TOFr in the PACU

Timeline

• Start date: 2014-06-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2014-08-27
• Last updated: 2014-08-27

Locations

25 sites across 1 country: Spain