NCT02225015

Cancer Prevention in Women With a BRCA Mutation

Cancer Prevention in Women With a BRCA Mutation: A Follow-up Genetic Counselling Intervention

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Women's College Hospital · Academic / Other
• Sex: Female
• Age: 35 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study aims to develop a follow-up telephone-based genetic counselling (FTGC) intervention for women with a BRCA1 or BRCA2 mutation who have received genetic counseling in the past. Typically, when women undergo genetic testing, they receive standard genetic counselling prior to testing in order to fully understand the procedure and associated implications. If a woman's genetic test results are positive for a mutation, cancer prevention options are then discussed with a counsellor. However, in Canada, there is currently no formal follow-up counselling for women with a BRCA mutation to provide ongoing guidance and support about latest risk reduction strategies. Standard care relies on women making contact for any follow-up questions or concerns they may have. As a result, these women might not have the most current information regarding genetic risk assessment and prevention options. Therefore, individuals are being asked to participate in this study to aid research about the efficacy of FTGC in women with a BRCA mutation.

Conditions

• BRCA1 Gene Mutation
• BRCA2 Gene Mutation
• Breast Cancer
• Ovarian Cancer

Interventions

Type	Name	Description
BEHAVIORAL	Follow-up Telephone Genetic Counselling	Individualized theoretical genetic counselling among women with BRCA mutations to assess the impact it has on the uptake of cancer prevention strategies.

Timeline

• Start date: 2015-01-01
• Primary completion: 2018-06-01
• Completion: 2019-06-01
• First posted: 2014-08-25
• Last updated: 2016-06-09

Locations

3 sites across 1 country: Canada