NCT02224586

Resting State Functional Magnetic Resonance Imaging Study of Jaundice Infants Before and After Light Treatment.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Hangzhou Normal University · Academic / Other
• Sex: All
• Age: 1 Day – 28 Days
• Healthy volunteers: Not accepted

Summary

It is just an observation study. The investigates want to explore the signal changes of resting state functional Magnetic resonance Imaging (fMRI) after light treatment in jaundice infants. Signal changes contain blood oxygenation level dependent (BOLD) and arterial spin labeling (ASL).Indicator of BOLD is amplitude of low-frequency fluctuation（ALFF).Indicator of ASL is cerebral blood flow (CBF). The investigates assume that the children with jaundice after light therapy, ALFF and CBF will change. Focus on the globus pallidus and subthalamic nuclei. The two brain regions were proved to be abnormal in MRI T1, T2 structure signal in kernicterus. Doctors observe the status of infants aside.Using monitoring probe can see clearly.

Detailed description

resting state fMRI scan light therapy the second time resting state fMRI scan

Conditions

• Jaundice

Interventions

Type	Name	Description
DEVICE	light treatment	clinical routine treatment according to the doctor's advice

Timeline

• Start date: 2014-08-01
• Primary completion: 2015-03-01
• Completion: 2015-07-01
• First posted: 2014-08-25
• Last updated: 2014-08-25

Locations

1 site across 1 country: China